Wynn's Hotelopened its doors in 1845 as a commercial boarding house under the ownership of Ms. Phoebe Wynn. Unfortunately, little is known of Phoebe Wynn except that her ownership lasted seven years. The Hotel's name changed to Telford’s during a successive ownership but in 1897 the name reverted to Wynn's when it was acquired by the Clarence Hotel Co. Ltd.On the 11th of November 1913 at a meeting held in the hotel, a decision was taken to establish 'The Irish Volunteers'. During the 1916 Rising a street barricade, which had been erected outside, Wynn's was set on fire by incendiary bullets. The fire spread from the barricade to the timber facings of the hotel and when guest and staff lives were threatened, they left the hotel under the protection of a makeshift white flag. As Dublin was under siege, fire fighters were unable to save the hotel and Wynn's was burned to the ground