Welcome to the Regina Hotel Guests Love Staying at the Holiday Inn Express Hotel & Suites Regina puts you in the heart of downtown Regina. Our hotel's location is ideal for both business and leisure guests who want to be close to everything Regina has to offer. When you choose our hotel in Regina, Canada you'll be close to the action. You can raise the stakes at Casino Regina, catch an IMAX film at the Saskatchewan Science Centre or explore the scenic beauty of the Wascana Centre. Are you a prospective student? We're just a short drive from the University of Regina, making us a favorite among Regina hotels for parents and families.When you're looking for hotels, our downtown Regina hotel is the smart choice for business travelers. You'll be in close proximity to Federated Co-operatives Ltd. and Innovation Place Research Park as well as many other companies