Holiday Inn Express Hotel, located along the Historic Route 66 in Barstow. Whether your travel plans bring you to Barstow for corporate, government travel, just passing through, visiting family and friends in Barstow, or you just need a leisurely night away from home, you will appreciate the service you will receive at Holiday Inn Express Hotel. The high speed Internet access, fitness center, and a business center are only a few of the features you will enjoy while staying at Holiday Inn Express Hotel Barstow. You will find the hotel location is convenient to all major highways in and out of Barstow.