Enjoy One of the Best Hotels in Athens; Tennessee Situated just off Interstate 75 halfway between Chattanooga and Knoxville; TN; Athens is a quiet city nestled in the foothills of the Great Smokey Mountains. Whether you're in town for business or leisure; we're sure you'll enjoy The Friendly City. Need a place to stay for your business trip? The Holiday Inn Express Athens; TN hotel is a great choice since we're within five miles of companies like Denso Manufacturing; Johnson Controls; ThyssenKrupp and the Mayfield Dairy headquarters. You can also use our Athens; TN hotel's 24-hour Business Center to prepare a presentation. Our 750-square-foot meeting room is great for hosting events; as well. If leisure activities bring you to Athens; TN; our hotel is the perfect jumping-off point to enjoy the surrounding area