Holiday Inn Express Hotel & Suites in Greenwood, Mississippi nestled in the heart of the Mississippi Delta & just minutes from historic downtown Greenwood, our non-smoking hotel offers both business and leisure travelers convenience, Southern hospitality and a great stay in one of the Delta's newest hotels. The hotel in Greenwood, Mississippi provides leisure travelers with easy access to nearby attractions like the Cottonlandia Museum and the Viking Range Corporation's renowned cooking school. Hotel also near the beautiful downtown area that is on the National Register of Historic Places, & city has the most Mississippi Blues Trail markers of any city in the state. During your stay at Greenwood, MS hotel, be sure to take advantage of on-site fitness center, guest laundry facilities and signature Express Start hot breakfast bar. Book your reservations now and enjoy excellent hotel deals and rates.