enter the gateway to the Delta...welcome to the Hampton Inn-Yazoo City, MS. The Hampton Inn Yazoo City hotel is the perfect gateway to the Delta. Enjoy views of rolling hills rising from the lush, fertile flatlands of the Mississippi Delta, the same scenic vistas that have charmed visitors for almost two centuries. From its colorful history, abundant forests and wildlife, to its modern city life, Yazoo City offers something for every visitor.Visit the Yazoo Historical Museum to learn more about our historic downtown, where Civil War gunboats once plied the waters of the long and winding Yazoo River. Also downtown, the Oakes African American Cultural Center, Triangle Cultural Center, Glenwood Cemetery and the Confederate Memorial Monument lure visitors year-round. Go antiquing or clothes shopping - it's all close to our Yazoo City, MS hotel! Take a drive outside Yazoo City and take in the verdant landscape, including catfish ponds, beautiful rivers, lakes and bayous. Enjoy the abundant