Conveniently located in the heart of beautiful Central California, the Hampton Inn & Suites San Luis Obispo can be accessed directly off of scenic Hwy. 101 and Los Osos Valley Rd. With championship golf courses, over 40 premium wineries, surfing, fishing, and hiking, the Hampton Inn & Suites San Luis Obispo makes a perfect destination for a family vacation or just a weekend getaway. Situated near Cal Poly University, Mission de Tolosa and legendary Hearst Castle, you are sure to leave with a magnificent impression of San Luis Obispo and the Hampton Inn & Suites. Our comfortable double queen or king guest rooms include a spacious work desk, free high-speed internet access, two phones with voice mail, 32-inch HD flat screen television. Enjoy our free hot breakfast every day. Stay connected with our free business center, keep up with your routine in our fitness center or relax in our indoor swimming pool and whirlpool. Earn rewards with Hilton HHonors Frequent Guest Program and rest easy